Alzheimer’s disease is a progressive neurological disorder that affects memory, thinking, and behavior. It is the most common cause of dementia, leading to a gradual decline in cognitive abilities. As brain cells deteriorate, individuals experience memory loss, confusion, and difficulty with daily tasks.
In 2025, an estimated 7.2 million Americans aged 65 and older are living with Alzheimer's dementia. This number represents 11% of the population in that age group. Globally, the number of people with dementia is projected to increase, with 82 million people living with dementia by 2030, and152 million by 2050. In 2025, healthcare and long-term care costs for people with Alzheimer's and other dementias in the US are projected to reach $384 billion. Additionally, nearly 12 million unpaid caregivers will provide an estimated 19.2 billion hours of care, valued at an additional $413 billion, according to the Alzheimer's Association.1
Historically, research has been focused on amyloid plaque, leading to billions of dollars wasted on drugs that did not improve the patients’ health continuum or extended life span. The latest “breakthrough” anti-amyloid antibody drugs do not improve cognition at all, they simply slow decline modestly, while exerting side effects that include brain hemorrhage, brain swelling, and death.
However, with the right tools, dementia is quickly becoming optional. No one needs to wait for symptoms to spiral. We now can detect risk early and act in time to prevent cognitive decline altogether.
Yes, cognitive decline is reversible as confirmed by peer-reviewed study Precision Medicine Approach to Alzheimer’s Disease: Successful Pilot Project 2
Gains can last for years, sometimes over a decade. This is not a short-term fix. It’s a new way forward as evidenced in the published case study Sustained Cognitive Improvement in Alzheimer’s Disease Patients Following a Precision Medicine Protocol3
The ReCODE 2.0 Protocol not only improves memory scores but also reverses the disease process. Brain scans show increased volume, improved blood flow, healthier brain waves, and better biomarkers. This protocol reduces the functional and biochemical changes that are associated with Alzheimer’s disease, not simply boosts cognition.
However, not every case is successful, especially when treatment begins too late or the full protocol isn’t followed. But this is true of any medical intervention from antibiotics to surgeries. That’s why early intervention is critical.
Therefore, we recommend that everyone over 35 get screened and begin a prevention program focusing on:
- Achieving insulin sensitivity
- Removing causes and resolving inflammation
- Supporting adaptive immunity
- Identifying and removing toxins (metallotoxins, organic toxins, and biotoxins)
- Optimizing nutrients and trophic factors
- Adjusting hormone levels
- Optimizing vascular health
- Healing the gut, optimizing microbiome (gut, oral, sinus)
- Introducing brain training
References
- New Alzheimer’s Association Report: Americans Want Early Diagnosis, Treatment and Are Open to Risk-Taking to Slow Disease Progression https://www.alz.org/news/2025/facts-figures-report-alzheimers-treatment
- Precision Medicine Approach to Alzheimer’s Disease: Successful Pilot Project, Kat Toups, Ann Hathaway, […],and Dale E. Bredesen, Journal of Alzheimer’s Disease Volume 88, Issue 4, 2022, Pages 1411-1421© 2022 – IOS Press. All rights reserved https://doi.org/10.3233/JAD-215707
- Sustained Cognitive Improvement in Alzheimer’s Disease Patients Following a Precision Medicine Protocol: Case Series, Dale E. Bredesen, Mary Kay Ross, and Stephen Ross, Biomedicines 2024, 12, 1776,https://doi.org/10.3390/biomedicines12081776
