Integrative Functional Medicine & Acupuncture Center

5-MTHF is the active form of folate necessary for mood, heart health, fetal development, and nerve support. This tissue-ready form of folate supports cellular methylation reactions. Many individuals don't get sufficient 5-MTHF because they have intestinal or liver dysfunction or because of they are among the three out of five Americans whose genetic makeup makes it difficult to convert folic acid into its active form. A deficiency of folic acid has been linked to low-birth-weight infants and neural tube defects, which is why the Centers for Disease Control recommends folic acid supplementation for all women of childbearing age. Since 5-MTHF also contributes to the production of serotonin, melatonin, dopamine, epinephrine, and norepinephrine, supplementation supports healthy mood. Suggested Use Take 1 capsule one to three times daily or as recommended by your healthcare provider.